EFFECT OF ALLOXAN TOXICITY ON THE GLYCOGEN CONTENT OF LIVER AND PANCREAS INSWISS ALBINO MICE
SUMAN SHARMA *
DEPARTMENT OF ZOOLOGY, PUNJABI UNIVERSITY, PATIALA-147002, INDIA
PRIYANKA BANSAL *
DEPARTMENT OF ZOOLOGY, PUNJABI UNIVERSITY, PATIALA-147002, INDIA
LALITA RAHEJA *
DEPARTMENT OF ZOOLOGY, PUNJABI UNIVERSITY, PATIALA-147002, INDIA
*Author to whom correspondence should be addressed.
Abstract
Alloxan is a diabetogenic agent. The pancreas and liver are found to be the major sites for its absorption in Swiss albino mice. It affects the production of insulin by damaging 3 cells of the pancreas. Insulin deficiency results in impairment of carbohydrate metabolism, resulting in hyperglycemic condition.
Keywords: Alloxan, diabetogenic agent, insulin, liver & pancreas, hyperglycemia