UTTAR PRADESH JOURNAL OF ZOOLOGY

A significant field of nanotechnology is the green synthesis of nanoparticles. In order to ascertain the effectiveness of synthesized silver nanoparticles (AgNps) against the parasite Raillietina tetragona, the current study focuses on the biosynthesis method of producing silver nanoparticles using biological compounds and evaluating their anthelmintic activities using aqueous and ethanolic extracts of Cucurbita maxima seeds and Punica granatum peel. Silver nanoparticles from 1 mM AgNO₃ solution and the Soxhlet apparatus are used to prepare the ethanolic extract of P. granatum peel and C. maxima seeds through aqueous and ethanolic extract. The sample turning brown indicates that silver nanoparticles have been produced. The UV-vis spectrophotometer and Fourier transform infrared (FTIR) spectrophotometer are used to characterize these produced silver nanoparticles. Different concentrations of Aqueous, Ethanolic, silver nanoparticles extract of C. maxima seeds and P. granatum peel are 2.5 mgml^-1, 5 mgml^-1, and 10 mgml^-1 were treated against cestode parasite R. tetragona. Albendazole is taken as standard and distilled water as control. A lower concentration, 2.5 mgml^-1 shows a slow paralytic and death rate of cestode worms compared to those in the higher concentration 10 mgml^-1. The study results showed that the death of the worms is dose-dependent manner. Results indicate that compared to the standard drug Albendazole, C. maxima seeds and P. granatum peel extracts are more effective Anthelmintic for chicken. After performing Anthelmintic activity on R. tetragona using both extracts time taken for the death of parasites in C. maxima seed extract is shorter than P. granatum peel. Based on the data observed, this study was concluded that C. maxima seed extract is more effective anthelmintic for chicken than P. granatum peel extract.