Study on the Impact of Aniline on Antioxidant Enzymes, Biochemical Contents and Hormonal Analysis on Testis of Male Albino Rat
Nayan Kumbhare
PGTD of Zoology, RTM Nagpur University, Nagpur-440033, Maharashtra, India.
Varsha Dhurvey *
PGTD of Zoology, RTM Nagpur University, Nagpur-440033, Maharashtra, India.
Vaibhavi Ingle
PGTD of Zoology, RTM Nagpur University, Nagpur-440033, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Aniline, common aromatic amine, has been linked to hormonal imbalances and reproductive toxicity.
Aim: This study examines its effects on body weight, organ weight, anti oxidant enzymes, and hormone levels and biochemical components in albino rats.
Method: The rats were categorized into a control group and an aniline-treated group. Body weight, testis weight, and serum testosterone, LH and FSH levels were measured, and anti oxidant enzymes were measured.
Results: Aniline treated rats showed reduced weight gain, lower testis weights, and decreased testosterone, LH and FSH levels. oxidative stress damages was induced in the testis.
Conclusion: Aniline exposure negatively impacts male reproductive health by altering hormone levels and testicular structure. Further research is needed to assess its relevance to human health.
Keywords: Aniline, lipid peroxidation, superoxide dismutase, catalase, LH, FSH, testosterone