Impacts of Monosodium Glutamate on Male Reproductive Health: A Study on Experimental Albino Rats
Harshada B. Pawar
Department of Zoology, RTM Nagpur University, Nagpur-440033, Maharashtra, India.
Varsha T. Dhurvey *
Department of Zoology, RTM Nagpur University, Nagpur-440033, Maharashtra, India.
Shyamla Katke
Department of Zoology, Brijlal Biyani Science College, Amravati-444601, Maharashtra, India.
Rashmi Urkude
Department of Chemistry, Shivaji Science College, Nagpur-441108, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Monosodium glutamate (MSG), a common food additive, has been linked to hormonal imbalances and reproductive toxicity. This study examines its effects on body weight, organ weight, testicular structure, and hormone levels in albino rats.
Methods: The rats were categorized into a control group and an MSG-treated group. Body weight, testis weight, and serum testosterone levels were measured, and testicular tissue was analyzed histologically.
Results: MSG-treated rats showed reduced weight gain, lower testis weights, and decreased testosterone levels. Histological analysis revealed structural damage to the testes.
Conclusion: MSG exposure negatively impacts male reproductive health by altering hormone levels and testicular structure. Further research is needed to assess its relevance to human health.
Keywords: Monosodium Glutamate (MSG), albino rats, testis, histology, reproductive toxicity, degenerative changes