Myconanosynthesis of Copper Oxide Nanoparticles from Talaromyces versatilis against Human Bacterial Pathogens
Sowbakkiyalakshmi B.
Department of Microbiology, Faculty of Science, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India.
Kolanjinathan K. *
Department of Microbiology, Faculty of Science, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Globally, there is a clinical problem caused by rising antibiotic resistance. The latest advances in biosynthesis have intrigued scientists and researchers as they investigate its potential against dangerous bacteria. The current emphasis is on myconanosynthesis, copper oxide nanoparticle (CuO NPs) characterization, and antibacterial efficacy. The extracellular biosynthetic approach we employed to create the CuO NPs was friendly to the environment. From agricultural soil samples, Talaromyces versatilis was isolated. They were comparing its 18s rDNA sequencing allowed for identification. Culture filtrate extracts of fungi were used as the reducing agents to synthesis the nanoparticles. XRD and DLS analysis were used to determine copper oxide nanoparticles (CuO NPs) size and material characteristics. When tested against Gram-positive and Gram-negative bacteria from that Salmonella paratyphi, Serratia sp., and Enterococcus fecalis myconanosynthesized copper oxide nanoparticles (CuO NPs) demonstrated a maximal zone of inhibition. Additionally, molecular in vivo research will aid in the creation of a novel wide-spectrum antibacterial drug.
Keywords: Antibiotic resistance, myconanosynthesis, Talaromyces versatilis, CuO Nps, XRD, DLS