A Comprehensive Study of Floating Drug Delivery Systems: Current Trends and Future Prospects
K. Venkata Gopaiah *
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
J. N. Suresh Kumar
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
M. Ramya Teja
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
T. Lokesh
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
D. Sai Sruthi
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
M. Roja
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
N. Rushitha
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
SK. Vahedunnisa
Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Palnadu, A.P.- 522 601, India.
*Author to whom correspondence should be addressed.
Abstract
In this review studies on FDDS are to collate the present written work with a particular study that states the principles & mechanism of floating of drugs to achieve bioavailability in gastric retention. This development of FDDS includes the physiological and formulation fluctuations that affect gastric retention, the process of designing single-unit to multiple-unit in floating systems, and the specification of formulation aspects included in that review study. This study reviews summates for laboratory techniques, and in animal studies in evaluating for performance and their functionating in floating systems. These systems are very helpful in resolving various faults that are triggered during the formulation development in the pharmaceutical dosage forms of FDDS.
Keywords: FDDS, single-unit, multiple-units