ANTIMICROBIAL ACTIVITY OF Dictyota dichotoma AND COPPER OXIDE NANOPARTICLES AGAINST SKIN INFECTION CAUSING MICROBES
K. GANESAN *
Department of Zoology, Nehru Memorial College (Autonomous), Affiliated Bharathidasan University, Puthanampatti, Tiruchirappalli, Tamil Nadu, India.
A. BOOPATHY RAJA
Department of Zoology, Nehru Memorial College (Autonomous), Affiliated Bharathidasan University, Puthanampatti, Tiruchirappalli, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
The skin is the largest organ of the human body. It acts as a physical barrier. The skin serves many functions particularly: protection, thermo-regulation, percutaneaous absorption, secretory and sensory. As the primary interface between the body and external environment, the skin provides the first line of defense against broad injury by microbial and chemical agents. Nanoparticles (NPs) are increasingly used to target bacteria as an alternative to antibiotics. nanoparticles is therefore regarded as next-generation antibiotics. The present study aimed to investigate the antimicrobial activity of copper oxide nanoparticles synthesized from Dictyota dichotoma (Aqueous extract) using biological a chemical methods against the skin causing microbes. All the tested samples (Copper acetate, Seaweed extract and copper oxide nanoparticles (B/C) showed different degrees of activities against the skin causing bacterial and fungal pathogens. copper oxide nanoparticles showed potent antimicrobial activity against skin infection-causing microbes strains like Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus pyogenes, Candida albicans (Fungus) and Trichophyton rubrum (Fungus).
Keywords: Dictyota dichotoma, Antimicrobial, Staphylococcus epidermidis, Streptococcus pyogenes, Staphylococcus aureus, Candida albicans, Trichophyton rubrum