A STUDY OF GLYCOSYLATED HEMOGLOBIN (HBA1C) IN ACUTE CORONARY SYNDROME
SHIVAMSH R. KASIREDDY
Department of Medicine, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India.
VIRENDRA C. PATIL
Department of Medicine, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India.
AVANTI J. DAMLE
Department of Medicine, Krishna Institute of Medical Sciences Deemed to be University, Karad, Satara, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Acute coronary syndrome (ACS) is a common emergency faced by physician during career. ACS is leading cause of mortality and morbidity in all over the world. Hence there is growing interest across the globe to find out various factors which could predict the prognosis of patient suffering from ACS. Objective: To study possible association between hemoglobin A1c(HbA1c) and admission glucose level identified during initial hospitalization in patients with acute coronary syndromes. Method: This hospital based prospective observational study was carried out for the period of 15 months from January 2017 to March 2018. A total of 100 patients who presented with ACS to the Emergency medicine Department under the Department of Medicine, Bharati Vidyapeeth Deemed University Medical College and Hospital, Sangli, Maharashtra were studied. The Results: Most of the patients were males (54%) and male to female ratio was 1.17:1. Most of the patients were (37%) aged between 61 to 70 years and 32% of the patients were aged between 51 to 60 years. The mean age was 62.36±9.89 years. Conclusion: Based on the above results it may be concluded that, admission glycated haemoglobin levels are associated with in hospital adverse events as well as outcome while outcome and adverse events were independent of blood sugar levels that is, random, fasting and post prandial blood sugar levels hence, blood sugar levels have limited prognostic value in patient with Acute coronary syndrome (ACS).
Keywords: Acute coronary syndrome (ACS), HbA1c, admission glucose level, haemoglobin, prandial blood sugar levels