EVALUATION OF In Vitro ANTI-INFLAMMATORY ACTIVITY OF FRESHWATER SNAIL
K. M. SRINANDHINIDEVI *
Department of Zoology, Quaid-E-Millath Government College for Women (Autonomous), Chennai-600002, India.
S. VIVEKA
Department of Zoology, Sethupathy Government Arts College, Ramanathapuram -623502, India.
*Author to whom correspondence should be addressed.
Abstract
Animal derived natural products contributed a major part in traditional medicine to prevent inflammation related diseases. The majority of clinically important medicines belong to steroidal or non-steroidal anti-inflammatory chemical therapeutic for the treatment of various inflammatory diseases and has severe side effects. Molluscs are rich in biologically active natural products that provide new potential sources of anti-inflammatory agents. The present study investigates the anti-inflammatory activity of freshwater snail (Pila globosa) through various in vitro models. Results of the present study concluded that snail shows potential anti-inflammatory activity was observed in a dose-dependent manner. The anti-inflammatory activity in higher doses (500mg/ml) of snail homogenate was similar to standard drug as Diclofenac sodium. This study is the scientific report that provides the convincing anti-inflammatory activity of snail evidence for scientific validity to its traditionally used by the local populace of south India.
Keywords: Freshwater snail, Pila globosa, In vitro anti-inflammatory