A STUDY ON ANALGESIC EFFECT OF Syzygium aromaticum IN ALBINO RATS USING HOT PLATE METHOD
SENTHIL KUMAR *
Department of Pharmacology, Sri Lakshmi Narayana Institute of Medical Sciences (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
. MAHESWARI
Department of Pharmacology, Sri Lakshmi Narayana Institute of Medical Sciences (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
G. JAYALAKSHMI
Department of Pharmacology, Sri Lakshmi Narayana Institute of Medical Sciences (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
The clove buds of Syzygium aromaticum were studied for analgesic activity on Albino rats. The results were compared with those of control by student t-test for individual samples; ANOVA followed by Post hoc multiple comparisons (LSD). The pain was induced by a single subcutaneous injection of 5% formalin in the paw of albino rats according to the method and by hot plate method and the analgesic activity of Syzygium aromaticum powder was studied based on the above two models. Pethidine and Ketorolac are the drugs used in this study to compare with Syzygium aromaticum powder. Syzygium aromaticum powder has shown a significant effect when compared with both drugs.
Keywords: Analgesic, indomethacin, albino rats, Syzygium aromaticum