PROTECTIVE EFFICACY OF Moringa oleifera AGAINST RADIATION AND MERCURY INDUCED BIOCHEMICAL CHANGES IN THE TESTES OF MICE
R. K. PUROHIT *
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
INDU BALA
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
HIMANI BHATI
Department of Zoology, Govt. Dungar College, Bikaner, India.
SHEFALI SOBTI
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
POOJA RANI
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
. ARTI
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
BIRBAL RAM
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
ARUNA CHAKRAWARTI
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
MANISHA AGARWAL
Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner, 334001, India.
*Author to whom correspondence should be addressed.
Abstract
In the present study, the protective effects of Moringa oleifera against radiation and mercury induced biochemical changes in the testes of mice have been taken into consideration. For the study, healthy Swiss albino mice were exposed to cobalt-60 gamma radiations with or without mercuric chloride treatment. The experimental groups were given Moring oleifera extract prior or individual or combined treatment of radiation and mercuric chloride. The value of total proteins, acid& alkaline phosphatase activities, DNA and RNA were observed in the form of increase or decrease. More severe changes were noted after combined treatment of radiation and mercuric chloride showing synergistic effect. An early and fast recovery was noticed in the Moringa treated experimental groups showing protection provided by the drug.
Keywords: Radiation, mercuric chloride, Moringa oleifera, testes and mice.